Von Willebrand disease: common bleeding symptoms, testing and treatment options.
- Common symptoms: nosebleeds, gum bleeding, easy bruising, and heavy menstrual bleeding.
- Diagnosis uses specialized von Willebrand factor level/function tests and factor VIII.
- Treatment may include tranexamic acid, desmopressin, or factor concentrates depending on type.
Von Willebrand disease (VWD) is the most common inherited bleeding disorder. Von Willebrand factor helps platelets stick to a damaged blood vessel and also stabilizes clotting factor VIII.
Many people have mild symptoms and only notice problems during dental procedures, surgery, or childbirth. Heavy periods are a common clue in women.
Treatment depends on the type and severity: tranexamic acid reduces bleeding, desmopressin can raise levels in some patients, and factor concentrates are used for major bleeding or surgery.